Amino Acid Profile of Polymeric Formula Based on Local Food for Stunting Prevention
Abstract
Adequacy energy and protein has a very strong potential to prevent stunting in children. The role of protein in preventing stunting can be focused more on the amino acid content of a food. Metabolomic research has proven that children who are stunted have lower serum concentrations of nine essential amino acids (tryptophan, isoleucine, leucine, valine, methionine, threonine, histidine, phenylalanine, lysine) compared to children who are not stunted ( p < 0.01). In addition, children who are stunted have low serum concentrations of conditionally essential amino acids (arginine, glycine, glutamine), non-essential amino acids (asparagine, glutamate, serine).This research was to ingredients the amino acid content (glutamic acid, phenylalanine, isoleucine, alanine, arginine, lysine, leucine, threonine, cystine, histidine) in polymeric formulas developed from local food. This research uses an experimental design in the laboratory with a Randomized Complete Factorial (RCF) with four factors, namely F1, F2, F3 and F4. The difference between the formulations of these four formulas is the addition of full cream milk (0%, 10%, 20% and 30% ) Analysis of the amino acid content was carried out at the SIG Laboratory Bogor. Results showed that the types of essential amino acids were complete and had a good quality amino acid score (SAA=100%). The limiting amino acid is the amino acid lysine. The digestible amino acid score in each formula is; F1 (65.72%), F2 (73.43%), F3 (81.53%), and F4 (85.25%).The results of the one-way ANOVA test showed that there were differences in amino acid content in the four formulas (P>0.05). Follow-up tests used the Tukey test to determine pairwise differences between groups and all groups, showing constant results. This shows that the treatment given, namely the addition of full cream milk, had a significant effect on the differences in amino acid content in the four formulas. Conclusion: The polymeric formula developed contains complete and good quality amino acids.
How to Cite
Views / Downloads
License
Authors who publish with Poltekita : Jurnal Ilmu Kesehatan agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
This work is licensed under a Creative Commons Attribution-ShareAlike 2.0 Generic License.
Poltekita : Jurnal Ilmu Kesehatan is licensed under a Creative Commons Attribution-Share Alike 4.0 International License
You are free to:
- Share, copy and redistribute the material in any medium or format
- Adapt, remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
References
Lenters, L., Wazny, K., & Bhutta ZA. Management of severe and moderate acute malnutrition in children. 2016; https://pubmed.ncbi.nlm.nih.gov/27227221/
Indonesian Ministry of Health. Regulation of the Minister of Health of the Republic of Indonesia Number 2 of 2020 concerning Child Anthropometric Standards. 2020;
Black, RE, Victora, CG, Walker, SP, Bhutta, ZA, Christian, P., De Onis, M., Ezzati, M., Grantham-McGregor, S., Katz, J., & Martorell R. Maternal and child undernutrition and overweight in low-income and middle-income countries. The Lancet. 2013; Available from: https://doi.org/https://doi.org/10.1016/S
RI K Ministry of Health. Riskendas 2018. In National Report Riskesndas 2018. 2018;
Das, JK, Salam, RA, Saeed, M., Kazmi, FA, & Bhutta ZA. Effectiveness of interventions for managing acute malnutrition in children under five years of age in low-income and middle-income countries: a systematic review and meta-analysis. 2020; https://pubmed.ncbi.nlm.nih.gov/31906272/
Hendrixson, D.T., Godbout, C., Los, A., Callaghan-Gillespie, M., Mui, M., Wegner, D., Bryant, T., Koroma, A., & Manary MJ. Treatment of severe acute malnutrition with oats or standard ready-to-use therapeutic food: a triple-blind, randomized controlled clinical trial. 2020; https://pubmed.ncbi.nlm.nih.gov/32179568/
FAO. Protein quality assessment in follow-up formula for young children and ready to use therapeutic foods. 2018;
Yi-Shen, Z., Shuai, S., & Fitz Gerald R. Mung bean proteins and peptides: Nutritional, functional and bioactive properties. Food & Nutrition Research. 2018; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846210/
Bröer, S., & Bröer A. Amino acid homeostasis and signaling in mammalian cells and organisms. 2017;
Richard D. Semba a,⁎, Michelle Shardell b, Fayrouz A. Sakr Ashour et all. Child Stunting is Associated with Low Circulating Essential Amino Acids. EBioMedicine. 2016; https://pubmed.ncbi.nlm.nih.gov/28546457/
Michaelsen, K.F., Hoppe, C., Roos, N., Kaestel, P., Stougaard, M., Lauritzen, L., Mølgaard, C., Girma, T., & Friis H. Choice of foods and ingredients for moderately malnourished children 6 months to 5 years of age. 2009; https://pubmed.ncbi.nlm.nih.gov/19998864/
Dahiya, PK, Linnemann, AR, Van Boekel, M., Khetarpaul, N., Grewal, R.B., & Nout MJR. Technological and nutritional potential. 2015; https://pubmed.ncbi.nlm.nih.gov/24915360/
Joye I. Protein digestibility of cereal products. 2019; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617089/
Manary, M., Callaghan, M., Singh, L., & Briend A. Protein quality and growth in malnourished children. Food and Nutrition Bulletin. 2016; https://pubmed.ncbi.nlm.nih.gov/26857118/
Braun, KVE, Erler, NS, Kiefte-de Jong, JC, Jaddoe, VW V, van den Hooven, EH, Franco, OH, & Voortman T. Dietary intake of protein in early childhood is associated with growth trajectories between 1 and 9 years of age. 2016;
Cahyono, E., & Rieuwpassa FJ. Amino acid analysis of several types of dried processed sea cucumbers in Sangihe Islands Regency. 2017; https://pubmed.ncbi.nlm.nih.gov/27733529/
Arsenault, J. E., & Brown, K. H. (2017). Effects of protein or amino-acidation on the physical growth of young children in low-income countries . Nutrition Reviews , 75 ( 9 ), 699–717. 10.1093/nutrit/nux027; https://pubmed.ncbi.nlm.nih.gov/28938793/
Arvianto, AA, Swastawati, F., & Wijayanti I. Effect of fortification of African catfish (Clarias gariepinus) meat meal on the amino acid lysine content in biscuits. Journal of Fishery Product Processing and Biotechnology. 2016; https://ejournal3.undip.ac.id/index.php/jpbhp/article/view/16019
Lima, MF de, Lima, CAR de, Dilelis, F., Gomes, AV da C., & Freitas LW de. Metabolizable energy and amino acid digestibility of soybean cake subjected to different dry extrusion temperatures for broilers. 2018; https://www.scielo.br/j/rbz/a/4RPxBJzTpYmG8NsDssPJH8y/?lang=en
Owino, VO, Irena, AH, Dibari, F., & Collins S. Development and acceptability of a novel milk‐free soybean–maize–sorghum ready‐to‐use therapeutic food (SMS‐RUTF) based on industrial extrusion cooking process. 2014; https://pubmed.ncbi.nlm.nih.gov/22462436/
Jacoeb, AM, & Lingga LAB. therapeutic food (SMS‐RUTF) based on industrial extrusion cooking process. 2012; http://onlinelibrary.wiley.com/doi/10.1111/j.1740-8709.2012.00400.x/abstract
Li, X., Zheng, S., & Wu G. Nutrition and metabolism of glutamate and glutamine in fish. Amino Acids. 2020; https://pubmed.ncbi.nlm.nih.gov/32405703/
Watford M. Glutamine and glutamate: Nonessential or essential amino acids? Animal Nutrition. 2015; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945979/
Pedroso, JAB, Zampieri, TT, & Donato Jr J. Reviewing the effects of Lleucine supplementation in the regulation of food intake, energy balance, and glucose homeostasis. 2015; https://pubmed.ncbi.nlm.nih.gov/26007339/
Similar Articles
Similar Articles
- Nurul Hidayah, Norliana Ekawati, Nur Ariska Ramadhana, Amelia Kartika, Culturally Integrated Behavior-Centered Design Using a Visual–Auditory–Kinesthetic Approach to Prevent Stunting , Poltekita: Jurnal Ilmu Kesehatan: Vol. 20 No. 1 (2026)
- Nurfatimah Nurfatimah, Priska Anakoda, Kadar Ramadhan, Christina Entoh, Sony Bernike Magdalena Sitorus, Lisda Widianti Longgupa, Perilaku Pencegahan Stunting pada Ibu Hamil , Poltekita: Jurnal Ilmu Kesehatan: Vol. 15 No. 2 (2021): August
- Fahmi Hafid, Nasrul Nasrul, A. Bungawati, Kadar Ramadhan, Risk Factors of Stunting in Children Under Two Years of Age in Donggala District Central of Sulawesi , Poltekita: Jurnal Ilmu Kesehatan: Vol. 17 No. 2 (2023): August
- Pahyuri Lubis, Mufdlilah, Assessment of the Feasibility of Using Mobile Application in Stunting prevention in Toddlers: Scoping Review , Poltekita: Jurnal Ilmu Kesehatan: Vol. 18 No. 2 (2024)
- Taqwin Taqwin, Mercy Joice Kaparang, Fitri Wahyuningtias, Kadar Ramadhan, Audiovisual Media Increases Stunting Prevention Knowledge Among Pregnant Women in The Working Area of Wani Health Center: Pretest, Posttest 1 dan Posttest 2 , Poltekita: Jurnal Ilmu Kesehatan: Vol. 16 No. 4 (2023): February
- Hesty Ayu Nurranti Ramadhani, Sudarto Ronoatmodjo, History of Chronic Energy Deficiency (CED) during Pregnancy and the Incidence of Stunting among Children Aged 0-59 Months in East Jakarta , Poltekita: Jurnal Ilmu Kesehatan: Vol. 17 No. 1 (2023): May
- Adni Ageng Lestari, Asa Azkatu Razaq, Moesijanti Y.E. Soekatri, Blood Pressure and Sodium Consumption: A Study of Fast Food Workers in Central Jakarta , Poltekita: Jurnal Ilmu Kesehatan: Vol. 18 No. 3 (2024)
- Fitri Fujiana, Vinka Theresia Pondaag, Aurelia Afra, Fannia Evy, Dzul Fadly, Potensi Pangan Fermentasi Tempe Dalam Mengatasi Kejadian Stunting di Indonesia , Poltekita: Jurnal Ilmu Kesehatan: Vol. 15 No. 2 (2021): August
- Ivan Elisabeth Purba, Leli Mariani Harahap , Rinawati Sembiring, Toni Wandra, Donal Nababan, Determinants of Stunting Among Children Under Two Years of Age in Batu Bara District, Indonesia , Poltekita: Jurnal Ilmu Kesehatan: Vol. 17 No. 2 (2023): August
- Mukhlidah Hanun Siregar, Hardinsyah, Katrin Roosita, Budi Iman Santoso, Validation of Thomas Formula in Estimation of Pre-Pregnancy Weight in Bogor City, Indonesia , Poltekita: Jurnal Ilmu Kesehatan: Vol. 19 No. 1 (2025)
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Aswita Amir, Rudy Hartono, Ronny Horax, Adriyani Adam, Exclusive Breastfeeding and Its Implications for Infant and Maternal Health, Knowledge, and Socioeconomic Well-being , Poltekita: Jurnal Ilmu Kesehatan: Vol. 19 No. 3 (2025)
