Pengaruh Suhu Penyimpanan Terhadap Jumlah Eritrosit Pada Transfusi Darah di Rumah Sakit Bank Darah RSUD Dr. Soedarso Pontianak
Abstract
Transfusi adalah proses pemindahan darah dari donatur kepada resipien, guna memperbaiki kondisi anemia dengan menggunakan darah yang berkualitas baik. Darah sebelum didonasikan akan disimpan pada refrigerator. Pada penyimpanan, darah akan mengalami berbagai perubahan komponen, termasuk jumlah trombosit, jumlah eritrosit dan kadar hemoglobin. Penyimpanan PRC didalam blood bank dengan suhu standar 10C - 60C mengurangi lisis, pendinginan diharapkan memperlambat metabolisme, mengurangi metabolisme glukosa, meningkatkan kelangsungan hidup PRC. Penyimpanan RBC dengan pendinginan cepat di bawah 150C dapat mencegah hilangnya diphosphoglycerate (DPG) dari RBC. Penelitian ini bertujuan untuk mengetahui pengaruh suhu 20C, 40C, dan 60C terhadap jumlah eritrosit pada darah tranfusi di Bank Darah Rumah Sakit Umum Daerah Dr. Soedarso Pontianak. Desain penelitian berbentuk eksperimen semu. Teknik sampling yang digunakan adalah purposive sampling, dengan jumlah sampel sebanyak 27 sampel, dilakukan dengan 3 perlakuan, 9 kali pengulangan dengan suhu 20C, 40C dan 60C. Perhitungan eritrosit menggunakan metode Automatic Cell Counter. Hasil uji statistic Kendall’s tau didapatkan nilai p (0,673) < α 0,05 berarti Ha ditolak. Sehingga, tidak ada pengaruh suhu penyimpanan suhu 20C, 40C dan 60C terhadap jumlah eritrosit pada darah donor sukarela di Bank Darah Rumah Sakit Umum Daerah Dr. Soedarso Pontianak
How to Cite
Views / Downloads
Files
License
Authors who publish with Poltekita : Jurnal Ilmu Kesehatan agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
This work is licensed under a Creative Commons Attribution-ShareAlike 2.0 Generic License.
Poltekita : Jurnal Ilmu Kesehatan is licensed under a Creative Commons Attribution-Share Alike 4.0 International License
You are free to:
- Share, copy and redistribute the material in any medium or format
- Adapt, remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
References
Hoffbrand A V, PAH M. Kapita Selekta Hematologi Edisi 6. Jakarta: EGC. Jakarta; 2013.
Franchini M, Marano G, Mengoli C, Pupella S, Vaglio S, Muñoz M, et al. Red blood cell transfusion policy: a critical literature review. Blood Transfus. 2017;15(4):307.
Bloch EM, Vermeulen M, Murphy E. Blood transfusion safety in Africa: a literature review of infectious disease and organizational challenges. Transfus Med Rev. 2012;26(2):164–80.
Janice R. Hubungan Pengetahuan Dan Sikap Tentang Donor Darah Dengan Tindakan Berdonor Pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara. Medan; 2009.
Astuti WD, Laksono AD. Keamanan Darah Di Indonesia Potret Keamanan Transfusi Darah di Daerah Tertinggal, Perbatasan dan Kepulauan. Surabaya Heal Advocacy. 2013;
Choudhury N, Tulsiani S, Desai P, Shah R, Mathur A, Harimoorthy V. Serial Follow-Up of Repeat Voluntary Blood Donors Reactive for Anti-HCV ELISA. Asian J Transfus Sci. 2011;5(1):26.
Adias TC, Moore-Igwe B, Jeremiah ZA. Storage Related Haematological and Biochemical Changes of CPDA-1 Whole Blood in a Resource Limited Setting. J Blood Disord Transfus. 2012;3(3):124.
Cluitmans JCA, Chokkalingam V, Jansen AM, Brock R, Huck WT, Bossman GJ. Alterations in Red Blood Cell Deformability during Storage: A Microfluidic Approach. BioMed Res Int. 2014;
Sowemimo-Coker SO. Red blood cell hemolysis during processing. Transfus Med Rev. 2002;16(1):46–60.
Alamsyah A, Widyaningrum D, Edward KSL. Hubungan Masa Simpan Packed Red Cell Dengan Kejadian Febrile Non Haemolytic TransFusion Reaction (FNHTRs). Media Med Muda. 2019;3(1).
Verma V, Donadee C, Gomez L, Zaretskaya M. Nonalcoholic Wernicke’s Encephalopathy Associated with Unintentional Weight Loss, Cholecystectomy, and Intractable Vomiting: The Role of Dual Thiamine and Corticosteroid Therapy. Kattah JC, Ikeda H, Berlit P, editors. Case Rep Neurol Med. 2014;2014:430729.
Chaudhary R, Katharia R. Oxidative Injury as Contributory Factor For Red Cells Storage Lesion During Twenty Eight Days of Storage. Blood Transfus. 2012;10(1):59.
D’Alessandro A, Kriebardis AG, Rinalducci S, Antonelou MH, Hansen KC, Papassideri IS, et al. An update on Red Blood Cell Storage Lesions, as Gleaned Through Biochemistry and Omics Technologies. Transfusion. 2015;55(1):205–19.
Al Audhah N, Suhartono E, Sardjono TW, Fitri LE. Duration of Storage Reduced Erythrocytes Profiles and Plasmodium Viability in Donor Blood. J Blood Med. 2021;12:87.
Bebesi T, Kitka D, Gaál A, Szigyártó IC, Deák R, Beke-Somfai T, et al. Storage conditions determine the characteristics of red blood cell derived extracellular vesicles. Sci Rep. 2022;12(1):1–13.
Suciati O. Pengaruh Lama Penyimpanan Darah Terhadap Kadar Hb, Jumlah Leukosit dan Jumlah Trombosit Pada Darah Donor. 2010.
Similar Articles
Similar Articles
- Hadina, Hadriani, Kartini, Putri Nurul Sakinah, Waktu Penggunaan Depo Medroxy Progesterone Acetate terhadap Peningkatan Indeks Massa Tubuh (IMT) Ibu: Timing of Depro Medroxy Progesterone Acetate Against Increased Body Mass Index (BMI) of Mother , Poltekita: Jurnal Ilmu Kesehatan: Vol. 13 No. 2 (2019): October
- Citra Wahyu Citra, Dina Dwi Nuryani, Christin Angelina Febriani, Pemanfaatan Vct Pada Orang Berisiko Tertular HIV/Aids Puskesmas Kota Bandar Lampung , Poltekita: Jurnal Ilmu Kesehatan: Vol. 15 No. 2 (2021): August
- Lely Cintari, Ni Nyoman Budiani, Listiana Ade Widya Ningtyas, Cersenlau Sugar (Cherry Kersen & Telang Ungu): A Potential Antidiabetic Agent for Pancreatic Beta-Cell Repair in Rats , Poltekita: Jurnal Ilmu Kesehatan: Vol. 17 No. 4 (2024): February
- Firdaus J. Kunoli, Azizah Saleh, Andi Nurhany, Amyadin Amyadin, Baharuddin Condeng, I Wayan Supetran, Moh. Fadli Dg. Patompo, Supriadi Abdul Malik, Bimbingan dan Pengujian Sukarela dengan Pendekatan Health Belief Model pada Waria di Sulawesi Tengah: Counseling And Voluntary Testing With The Health Belief Model Approach To Waria In Central Sulawesi , Poltekita: Jurnal Ilmu Kesehatan: Vol. 14 No. 2 (2020): October
- Wijianto Wijianto, Rugaya Said, Nitro Galenso, Status Gizi Ibu Hamil dan Kepatuhan Minum Multifle Micronutrien Di 10 Desa Lokus Stunting Di Kabupaten Banggai , Poltekita: Jurnal Ilmu Kesehatan: Vol. 16 No. 1 (2022): May
- Husnul Khatimah, Saifuddin Sirajuddin, Zainal, PENGARUH PEMBERIAN SUSU BEKATUL TERHADAP KONSENTRASI KOLESTEROL DAN TRIGLISERIDAPADA TIKUS PUTIH WISTAR DIABETES , Poltekita: Jurnal Ilmu Kesehatan: Vol. 12 No. 2 (2018): October
- Husnul Khotimah, Hanum Sasmita, Faktor yang berhubungan dengan Kejadian Bayi Berat Lahir Rendah (BBLR) di Ruang Perinatologi RSUD Drajat Prawiranegara : Factors related to Low Birth Weight (LBW) in the Perinatology Room Drajat Prawiranegara Regional Hospital , Poltekita: Jurnal Ilmu Kesehatan: Vol. 14 No. 2 (2020): October
- Rahmi Permatasari, Andi Liliandriani, The Implementasi Kegiatan Imunisasi Posyandu dengan Menggunakan Juknis Imunisasi pada masa Pandemi Covid -19 , Poltekita: Jurnal Ilmu Kesehatan: Vol. 15 No. 3 (2021): November
- Herawati Herawati, Sandy Novryanto Sakati, Zulfikar Sumarto, Kualitas Bakteriologis Pada Peralatan Makan Di Warung Makan Kadompe Di Kota Luwuk Kabupaten Banggai , Poltekita: Jurnal Ilmu Kesehatan: Vol. 16 No. 2 (2022): August
- Eko Naning Sofyanita, Mochamad Rizal Maulana, Puji Lestari, Burhannudin, The Effect of Robusta Coffee (Coffea canephora) on the Expression of SOD and Nrf-2 in Diabetes Mellitus condition (Animal Model) , Poltekita: Jurnal Ilmu Kesehatan: Vol. 18 No. 3 (2024)
You may also start an advanced similarity search for this article.
