The Association Between Age and Parity with the Incidence of Cervical Cancer: A Case-Control Study
https://doi.org/10.33860/jbc.v7i3.4285
Keywords:
Cervical Cancer, Parity, AgeAbstract
Background: Cervical cancer is one of the leading causes of mortality among women worldwide and ranks second in Indonesia after breast cancer. Data from Dr. H. Abdul Moeloek General Hospital in 2024 recorded 255 hospitalized patients diagnosed with cervical cancer, equivalent to approximately 0.57% of total visits. Risk factors associated with cervical cancer incidence include age and parity, which may influence susceptibility to persistent HPV infection and cervical cell changes.
Methods: This study employed a quantitative case-control design. The study population consisted of all 255 inpatients diagnosed with cervical cancer in 2024. A total of 192 respondents were selected using random sampling, comprising 96 cases (with cervical cancer) and 96 controls (without cervical cancer). Data were analyzed using univariate and bivariate methods with the Chi-Square test.
Results: The Chi Square test results show a significant relationship between age and cervical cancer incidence (p=0.001; OR=44.922), as well as a relationship between parity and cervical cancer incidence (p=0.001; OR=103.400). Women who are older and have higher parity are at greater risk of developing cervical cancer than those who are at lower risk.
Conclusion: There is a significant association between age <20/>35 years and grandmultiparity with the incidence of cervical cancer. Women of reproductive age are advised to increase their awareness of early detection through regular IVA (Visual Inspection with Acetic Acid) or Pap smear examinations at least every 3 years. Health workers are expected to strengthen health promotion programs on healthy reproductive age and safe number of births in order to reduce the incidence of cervical cancer.
Downloads
References
Arieska, P. K., & Herdiani, N. (2018). Pemilihan Teknik Sampling Berdasarkan Perhitungan Efisiensi Relatif. Jurnal Statistika, 6(2), 166–171. Retrieved from https://jurnal.unimus.ac.id/index.php/statistik/article/view/4322/4001
Astri Nadia Hidayat, Novita Ariani, I. R. B. (2021). Gambaran Faktor Risiko Pasien Kanker Serviks di RSUP Dr . M . Djamil. 425–430. https://doi.org/https://doi.org/10.25077/jikesi.v1i3.239
Biostatistik, J., Kesehatan, I., & Ramadhaningtyas, A. (2020). Hubungan Seksual Usia Dini Dapat Meningkatkan Risiko Kanker Serviks. Jurnal Biostatistik, Kependudukan, Dan Informatika Kesehatan, 1(1). https://doi.org/10.7454/bikfokes.v1i1.1004
Burd, E. M. (2003). Human papillomavirus and cervical cancer. Clinical Microbiology Reviews, 16(1), 1–17. https://doi.org/10.1128/CMR.16.1.1-17.2003
Dinas Kesehatan Pemerintah Kota Bandar Lampung. (2021). Profil Kesehatan Kota Bandar Lampung Tahun 2021. Dinas Kesehatan Pemerintah Kota Bandar Lampung, 182. Retrieved from https://dinkeskotabalam.com/prof/DINAS_KESEHATAN.pdf
Ekawati, F. M., Listiani, P., Idaiani, S., Thobari, J. A., & Hafidz, F. (2024). Cervical cancer screening program in Indonesia: is it time for HPV-DNA tests? Results of a qualitative study exploring the stakeholders’ perspectives. BMC Women’s Health, 24(1), 125. https://doi.org/10.1186/s12905-024-02946-y
Ge’e, M. E., Lebuan, A., & Purwarini, J. (2021). Hubungan antara Karakteristik, Pengetahuan dengan Kejadian Kanker Serviks. Jurnal Keperawatan Silampari, 4(2), 397–404. https://doi.org/10.31539/jks.v4i2.1668
Globocan. (2024). Global Cancer Observatory. 2022, 2024–2025. https://doi.org/10.1002/ijc.33588.
Gravitt, P. E., Paul, P., Katki, H. A., Vendantham, H., & Ramakrishna, G. (2010). Effectiveness of VIA , Pap , and HPV DNA Testing in a Cervical Cancer Screening Program in a Peri-Urban Community in Andhra Pradesh , India. 5(10). https://doi.org/10.1371/journal.pone.0013711
Husnah, A. (2018). Hubungan paritas dan umur dengan kejadian kanker serviks di RSU PKU Muhammadiyah Bantul Yogyakarta. Naskah Publikasi Universitas ‘Aisyiyah Yogyakarta, 1–8. Retrieved from http://digilib.unisayogya.ac.id/4149/
Idris, I. M., Angka, R. N., Christina, S., Mexcorry, E., Kedokteran, F., Kristen, U., … Krida, U. K. (2020). Aktivitas Seksual Usia Dini dan Paritas Tinggi Meningkatkan Risiko Kanker Serviks Early Sexual Activity and High Parity Increase The Risk for Cervical Cancer. 27(3), 306–316. https://doi.org/https://doi.org/10.36452/jkdoktmeditek.v27i3.1997
Jaelani, S. H., Kurniati, N., Rokhanawati, D., & Yogyakarta, A. (2021). Deteksi dini kanker serviks pada wanita usia subur : A scoping review mengunakan Framework. 5(2), 117–126. https://doi.org/https://doi.org/10.32536/jrki.v5i2.207
Khabibah, U., Adyani, K., & Rahmawati, A. (2022). Faktor Risiko Kanker Serviks: Literature Review. Faletehan Health Journal, 9(3), 270–277. https://doi.org/10.33746/fhj.v10i03.354
Kusika, S. Y., & Sakti, P. M. (2025). Role of Birth Companions in Influencing Labor Duration on Partus Mother. 7(1), 23–28. https://doi.org/10.33860/jbc.v7i1.3876
Lestari, A. I., & Hidayat, B. (2019). Deteksi Dini Conventional Smear dan Liquid Based Cytology dalam Upaya Pencegahan Kanker Serviks: Systematic Review. Jurnal Kesehatan Reproduksi, 6(2), 71–78. Retrieved from https://jurnal.ugm.ac.id/jkr/article/view/42627/25399
Liu, J., Li, D., Chen, H., Wang, H., Wada, Y., Kummu, M., … Ciais, P. (2024). Timing the first emergence and disappearance of global water scarcity. Nature Communications, 15(1), 1–11. https://doi.org/10.1038/s41467-024-51302-z
Monica Trifitriana, Rizal Sanif, & Syarif Husin. (2021). Faktor Risiko Kanker Serviks Pada Pasien Rawat Jalan dan Rawat Inap Di Departemen Obstetri dan Ginekologi RSUP Dr. Mohammad Hoesin Palembang. Biomedical Journal of Indonesia : Jurnal Biomedik Fakultas Kedokteran Universitas Sriwijaya, 3(1), 11–19. Retrieved from https://bji-fk.ejournal.unsri.ac.id/index.php/bji/article/download/2/2
Nida Mayrita, S., & Handayani, N. (2018). Hubungan Antara Paritas Dengan Kejadian Kanker Serviks Di Yayasan Kanker Wisnuwardhana Surabaya. Journal of Health Sciences, 8(1), 1–7. https://doi.org/10.33086/jhs.v8i1.212
Prasasty, G. D., & Legiran. (2023). Studi Kasus Kontrol. Jurnal Kedokteran Syiah Kuala, 23(1), 232–236. Retrieved from https://jurnal.usk.ac.id/JKS/article/view/25496
Putri, D., Ningsih, S., Pramono, D., & Nurdiati, D. S. (2016). kanker serviks di RSUP Dr . Sardjito Yogyakarta. (3). Retrieved from https://media.neliti.com/media/publications/163928-ID-faktor-faktor-yang-berhubungan-dengan-ke.pdf
Rio, S., & Sri Tyas Suci, E. (2017). Persepsi Tentang Kanker Serviks Dan Upaya Prevensinya Pada Perempuan Yang Memiliki Keluarga Dengan Riwayat Kanker. Jurnal Kesehatan Reproduksi, 4(3), 159–169. Retrieved from https://jurnal.ugm.ac.id/jkr/article/view/36511/21289
Sigalingging, V. T., Lubis, R., & Andayani, L. S. (2021). Pengaruh Riwayat Keluarga Dan Riwayat Aborsi Terhadap Kejadian Kanker Payudara Di Rsup H.Adam Malik Medan Tahun 2020. Jurnal Health Sains, 2(2), 259–265. https://doi.org/10.46799/jhs.v2i2.115
Subhaktiyasa, P. G. (2024). Menentukan Populasi dan Sampel : Pendekatan Metodologi Penelitian Kuantitatif dan Kualitatif. 9, 2721–2731. https://doi.org/https://doi.org/10.29303/jipp.v9i4.2657
Sudartinah, Mediastuti, F., & Kasjono, H. S. (2022). Effective Educational Media for Health Promotion to Preventing Cervical Cancer of Women Reproductive in 2019–2022: A Systematic Literature Review. Jurnal Kebidanan Kestra (Jkk), 5(1), 29–36. https://doi.org/10.35451/jkk.v5i1.1187
Sulistyawati, D., Faizah, Z., & Kurniawati, E. M. (2020). An Association Study of Cervical Cancer Correlated with The Age of Coitarche in Dr . Soetomo Hospital Surabaya. 14(March), 3–7. Retrieved from 10.33371/ijoc.v14i1.639
Vieira, R., Mariani, J. N., Huynh, N. P. T., Stephensen, H. J. T., Solly, R., Tate, A., … Goldman, S. A. (2024). Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain. Nature Biotechnology, 42(5), 719–730. https://doi.org/10.1038/s41587-023-01798-5
Wanda, M., Oktavia, N. S., & Yusefni, E. (2018). Faktor-faktor yang berhubungan dengan kanker serviks DR.M Djamil Padang 2017. 2(April), 79–85. https://doi.org/https://doi.org/10.33757/jik.v2i1.82
WHO. (2015). Kejadian Kanker payudara dan kanker serviks. Retrieved from https://platform.who.int/docs/default-source/mca-documents/policy-documents/law/IDN-RH-47-02-LAW-2015-ind-MoH-Regulation-34-2015---Countermeasures-of-Breast-and-Cervical-Cancer.pdf
Zeta, N. K. Z. N. K., Oktarlina, R. Z., Ramdini, D. A., & Wardhana, M. F. (2023). Relationship between parity and cervical cancer: literature review. Medical Profession Journal of Lampung, 13(4), 490–494. Retrieved from http://journalofmedula.com/index.php/medula/article/view/739
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Susilawati, Nasywa Ardelia Putri, Ana Mariza, Sunarsih (Author)

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with Jurnal Bidan Cerdas agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

This work is licensed under a Creative Commons Attribution-Share Alike 4.0 International License
You are free to:
- Share, copy and redistribute the material in any medium or format
- Adapt, remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.

